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The number of offers should remain: Monkeypox virus under the electron microscope. On the left – mature viruses, on the right – not yet.
The main concern of doctors is that the virus could become established in regions where it is not endemic. WHO Director-General Tedros Adhanom Ghebreyesus told a briefing in Geneva that there is a real risk of monkeypox spreading to non-endemic countries, or places where the disease is imported rather than endemic. This year, the World Health Organization has recorded 1600 confirmed cases of monkeypox and 1500 suspected cases in nearly 40 countries. Hebrewsus told journalists that this outbreak is unusual because cases of the disease have been recorded in several countries outside of Central and West Africa, where the disease is endemic. On June 23, WHO plans to convene an emergency committee to assess whether this outbreak constitutes a public health emergency of international concern.
Spain has set up laboratories to test potential cases of monkeypox. The highest number of cases in Europe has been reported in Spain, Portugal and the United Kingdom. At the same briefing, Rosemund Lewis, WHO’s project manager for monkeypox, noted that world health leaders are not rushing to declare the monkeypox outbreak a pandemic because the coronavirus pandemic is far from over and the logistics of dealing with two pandemics simultaneously are extraordinarily complex. According to her, there is some optimism in the fact that this strain of monkeypox is rarely fatal and that doctors know how to treat it with antiviral drugs and supportive therapy. The number of cases should remain the same. In African countries where it is endemic, 72 deaths have been recorded, compared with none in non-endemic countries.
Albert Burla at the opening of Pfizer’s new center in Greece. He believes that the development of vaccines against coronaviruses is far from over and that this pandemic has shown the importance of investing in scientific development. We explain quickly, simply, and clearly what happened, why it matters, and what happens next. Episodes End of story Promotional Podcasts At the same time, Pfizer Chairman and CEO Albert Bourla said that new strains of Covid-19, against which current vaccines have little or no effect, pose a much greater threat to global public health than the monkeypox outbreak. “We are closely monitoring the spread of monkeypox, but it does not appear to be contagious enough to become a pandemic,” he said. “I think the main concern remains COVID.” A week ago, the World Health Organization announced that the decline in cases and deaths from Covid-19 continues. The total number of registered deaths has fallen by more than 90% from its peak earlier this year. However, there are concerns that because many countries are not tracking new coronavirus cases as diligently as they used to, the actual number of infected people may be higher than the official figures.
Mutation of Omicron compared to the original strain with indication of substitutions (yellow), deletions (red) and insertions (green). Data from WHO. There is concern that the UK is now at the beginning of a new wave of COVID infections caused by the BA.4 and BA.5 variants. It is also possible that these strains are more likely to affect lung tissue than the upper respiratory tract, making them potentially more dangerous. On May 20, British doctors recognized it as a variant of concern (VOC). They were responsible for the majority of cases during the second wave of COVID-19 infections in South Africa in May of this year.
Covid-19 variants: Alpha, Beta, Gamma, Delta, Omicron. Omicron is currently the most virulent, but also the mildest. However, it is not impossible that it could mutate into more pathogenic forms. According to a study by scientists at Imperial College London, published June 14 in the journal Science, immunity to new Omicron variants developed as a result of previous vaccination and exposure to this variant is not as good as hoped. The common assumption was that being infected with COVID would give you a natural boost of immunity that would allow you to better deal with the infection in the future. However, as it turned out, Omicron provides a weak natural immunity against re-infection with the same Omicron, even in people who have been vaccinated three times. For those who have received the triple vaccination but have not been infected with previous variants of the coronavirus, the disease caused by the Omicron strain has provided an increase in immunity to previous variants (Alpha, Beta, Gamma, Delta, and the original ancestral strain), but to a lesser extent to Omicron itself.
In the UK, COVID pandemic restrictions ended in February. However, there is no guarantee that they will never be reinstated, especially if Omicron mutates into more pathogenic strains. According to the scientists, their conclusions explain the wave of reinfections at a time when the Omicron variant was the most common strain in the UK. Immunity gained through vaccination or previous illness was hardly transferred to the Omicron strain. However, the authors of the study emphasize that vaccination still provides protection against serious illness and death. Professor Rosemary Boyton of the Department of Infectious Diseases at Imperial College noted that Omicron infection does not provide a strong boost of immunity against future Omicron reinfection. She also confirmed that the concern stems from Omicron’s potential ability to mutate into a more pathogenic, or disease-causing, strain.
In the United Kingdom, the vaccination program has covered the vast majority of the population, but only the elderly and those with weakened immune systems have received the fourth dose of the vaccine. And Professor Danny Altman of the Department of Immunology emphasized that Omicron masks itself much better than previous strains and the immune system cannot remember it. These two factors can cause the body’s immune system to be unable to deal with more dangerous Omicron variants when they arise. It is important to remember that because the coronavirus in all its variations is relatively new and still poorly understood, no one can say for sure how it will affect the health of those who have had the disease in the long term.